Injectable and tunable poly(ethylene glycol) analogue hydrogels based on poly(oligoethylene glycol methacrylate).

Injectable and tunable poly(ethylene glycol) analogue hydrogels based on poly(oligoethylene glycol methacrylate).

Chemical communications (Cambridge, England) (2014-02-18)

Niels M B Smeets, Emilia Bakaic, Mathew Patenaude, Todd Hoare

ABSTRACT

Injectable PEG-analogue hydrogels based on poly(oligoethylene glycol methacrylate) have been developed based on complementary hydrazide and aldehyde reactive linear polymer precursors. These hydrogels display the desired biological properties of PEG, form covalent networks in situ following injection, and are easily modulated for improved control over their functionality and physiochemical properties.

MATERIALS

Product Number

Brand

Product Description

901777

Sigma-Aldrich

Poly(M(EO)2MA:Poly(OEGMA), (90:10), aldehyde functionalized, 25 wt% solution in water

901776

Sigma-Aldrich

Poly(OEGMA), hydrazide functionalized, 25 wt% solution in water

901546

Sigma-Aldrich

Poly(M(EO)2MA:Poly(OEGMA) 90:10, hydrazide functionalized, 25 wt. % (solution in water)