- A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots.
A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots.
Chemical communications (Cambridge, England) (2012-05-01)
Oleg Kovtun, Emily J Ross, Ian D Tomlinson, Sandra J Rosenthal
PMID22543630
ABSTRACT
Here we present the development and validation of a flow cytometry-based dopamine transporter (DAT) binding assay that uses antagonist-conjugated quantum dots (QDs). We anticipate that our QD-based assay is of immediate value to the high throughput screening of novel DAT modulators.
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