SAB4200612

Monoclonal Anti-EXOC6 antibody produced in mouse

~1.0 mg/mL, clone 15S2G6, purified immunoglobulin

• Synonym(s): Anti-EXOC6A, Anti-RP11-348J12.4, Anti-SEC15-like 1, Anti-SEC15-like protein 1, Anti-SEC15-like protein 3, Anti-SEC15, Anti-SEC15L1, Anti-SEC15L3, Anti-SEC15L, Anti-Sec15p, Anti-exocyst complex component Sec15A
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 200
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 15S2G6, monoclonal
• form: buffered aqueous solution
• mol wt: antigen ~90 kDa
• species reactivity: canine, rat, monkey, bovine, human
• concentration: ~1.0 mg/mL
• technique(s): flow cytometry: 20 μg/test using A549 cells; immunoblotting: 0.5-1.0 μg/mL using NT2/D1 total cell extracts; immunofluorescence: 20 μg/mL using PC12 or A549 cells
• isotype: IgG1
• UniProt accession no.: Q8TAG9
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... EXOC6(50556)

Description

General description

Monoclonal Anti-EXOC6 (mouse IgG1 isotype) is derived from the hybridoma 15S2G6 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a recombinant protein corresponding to full-length rat brain EXOC6 subunit. Exocyst complex component 6 (EXOC6) is located on the human chromosome at 10q23.33.

Immunogen

a recombinant protein corresponding to full-length rat brain EXOC6 subunit.

Application

Monoclonal Anti-EXOC6 antibody has been used in

• immunoblotting
• immunofluorescence
• flow Cytometry
• immunocytochemistry

Biochem/physiol Actions

Exocyst complex component 6 (EXOC6) has been shown to interact with the Rab11 (Ras-related protein), a GTPase that regulates both biosynthetic and endocytic traffic. This interaction results in endocytic trafficking directed toward the apical and basolateral poles of polarized cells.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable