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247480

Sigma-Aldrich

Domiphen bromide

97%

Synonym(s):

(Dodecyldimethyl-2-phenoxyethyl)ammonium bromide

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About This Item

Linear Formula:
CH3(CH2)11N(CH3)2(CH2CH2OC6H5)Br
CAS Number:
538-71-6
Molecular Weight:
414.46
EC Number:
208-702-0
MDL number:
MFCD00011769
UNSPSC Code:
12352112
PubChem Substance ID:
24854870
NACRES:
NA.22

Assay

97%

form

powder

mp

117-119 °C (lit.)

SMILES string

[Br-].CCCCCCCCCCCC[N+](C)(C)CCOc1ccccc1

InChI

1S/C22H40NO.BrH/c1-4-5-6-7-8-9-10-11-12-16-19-23(2,3)20-21-24-22-17-14-13-15-18-22;/h13-15,17-18H,4-12,16,19-21H2,1-3H3;1H/q+1;/p-1

InChI key

OJIYIVCMRYCWSE-UHFFFAOYSA-M

General description

Domiphen bromide (DMP) is a quaternary ammonium compound that belongs to the class of phenol ethers. It can be used as a cationic surfactant.

Application

  • Domiphen Bromide in Antimicrobial Applications: A clinical trial assessed the effectiveness of a mouthwash containing Domiphen Bromide among other quaternary ammonium compounds, showcasing its ability to significantly reduce gingivitis, supporting its use in dental health products (Rosa and Sturzenberger, 1976).
  • Toxicity and Safety Profile of Domiphen Bromide: A recent study explored the proarrhythmic effects induced by Domiphen Bromide in both in vitro and in vivo models, providing vital safety information crucial for its use in pharmaceutical applications (Long et al., 2021).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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