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Merck

SMC3

structural maintenance of chromosomes 3

Synonyms:
BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
Species:
UniProtKB ID:
Gene ID:
  • Human(9126) Summary: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]
  • Mouse(13006) structural maintenance of chromosomes 3
  • Rat(29486) structural maintenance of chromosomes 3
  • naked mole-rat(101725969) structural maintenance of chromosomes 3
  • Thale Cress(834917) structural maintenance of chromosomes protein 4
  • Zebrafish(324475) structural maintenance of chromosomes 3
  • chicken(395188) structural maintenance of chromosomes 3
  • dog(486886) structural maintenance of chromosomes 3
  • Horse(100059335) structural maintenance of chromosomes 3
  • domestic cat(101093211) structural maintenance of chromosomes 3
  • cow(281729) structural maintenance of chromosomes 3
  • sheep(101119007) structural maintenance of chromosomes 3
  • Domestic Rabbit(100354309) structural maintenance of chromosomes 3
  • domestic guinea pig(100726965) structural maintenance of chromosomes 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Rabbit anti-SMC3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-CSPG6 antibody produced in mouse, clone 1G1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-SMC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CSPG6 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-SMC3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse SMC3,
Species
mouse
MISSION® esiRNA, targeting human SMC3,
Species
human