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Merck

NLRP2

NLR family, pyrin domain containing 2

Synonyms:
CLR19.9, NALP2, NBS1, PAN1, PYPAF2
Species:
Human NLRP2 (55655), Mouse Nlrp2 (232827), cow NLRP2 (100301026), dog NLRP2 (484304), sheep NLRP2 (101123321), Domestic Rabbit NLRP2 (100344125), domestic cat NLRP2 (101093815), Horse NLRP2 (100055187)
UniProtKB ID:
Q9NX02, B4DZL7, I3L0G4, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6
Gene ID:
  • Human(55655) Summary: NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]
  • Mouse(232827) NLR family, pyrin domain containing 2
  • cow(100301026) NLR family, pyrin domain containing 2
  • dog(484304) NLR family, pyrin domain containing 2
  • sheep(101123321) NLR family, pyrin domain containing 2
  • Domestic Rabbit(100344125) NLR family, pyrin domain containing 2
  • domestic cat(101093815) NLR family, pyrin domain containing 2
  • Horse(100055187) NLR family, pyrin domain containing 2

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1403297
Monoclonal Anti-NLRP2 antibody produced in mouse, clone 1B10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
SAB1411064
Anti-NLRP2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
HPA020765
Anti-NLRP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
HPA021183
Anti-NLRP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
SAB2501748
Anti-NLRP2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
EHU086731
MISSION® esiRNA, targeting human NLRP2,
Species
human