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Merck

CES1

carboxylesterase 1

Synonyms:
ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1
Species:
UniProtKB ID:
Gene ID:
  • Human(1066) Summary: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
  • naked mole-rat(101726140) carboxylesterase 1
  • cow(512098) carboxylesterase 1 (monocyte/macrophage serine esterase 1)
  • domestic cat(493774) carboxylesterase 1
  • dog(403643) carboxylesterase 1
  • chicken(415786) carboxylesterase 1 (monocyte/macrophage serine esterase 1)

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ELISA

Product Number
Description
Species
Human Carboxylesterase 1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-hCE-1/CES1 Antibody, clone 1D4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-CES1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CES1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-CES1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-CES1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
2-Decanone, 98%,
Species
human
2,3-Pentanedione, natural, ≥96%, FG,
Species
human
2,2′-Dichlorobenzil, 97%,
Species
human
1,2-Cyclohexanedione, 97%,
Species
human
2,3-Butanedione, 97%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CES1,
Species
human