BCL2A1
BCL2-related protein A1
Synonyms:
ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1
Species:
Human BCL2A1 (597), Rat Bcl2a1 (170929), cow BCL2A1 (282151), chicken BCL2A1 (395673), dog BCL2A1 (488770), naked mole-rat Bcl2a1 (101702935), domestic cat BCL2A1 (768283), sheep BCL2A1 (101114560), domestic cat BCL2A1 (101086480), domestic guinea pig Bcl2a1 (100732983)
UniProtKB ID:
Gene ID:
- Human(597) Summary: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(170929) BCL2-related protein A1
- cow(282151) BCL2-related protein A1
- chicken(395673) BCL2-related protein A1
- dog(488770) BCL2-related protein A1
- naked mole-rat(101702935) BCL2-related protein A1
- domestic cat(768283) BCL2-related protein A1
- sheep(101114560) BCL2-related protein A1
- domestic cat(101086480) BCL2-related protein A1
- domestic guinea pig(100732983) BCL2-related protein A1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-BCL2A1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, pig
Application
ELISA
western blot
western blot
Anti-BCL2A1/BFL-1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
camelidae, bat, bovine, chimpanzee, human
Application
immunohistochemistry
western blot
western blot
Anti-BCL2A1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-BCL2A1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-BFL-1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species