ASIC3
acid-sensing (proton-gated) ion channel 3
ACCN3, DRASIC, SLNAC1, TNaC1
Human ASIC3 (9311), Mouse Asic3 (171209), Rat Asic3 (286920), naked mole-rat Asic3 (101722725), domestic cat ASIC3 (101096970), domestic guinea pig Asic3 (100731464), sheep ASIC3 (101113062)
- Human(9311) Summary: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
- Mouse(171209) acid-sensing (proton-gated) ion channel 3
- Rat(286920) acid-sensing (proton-gated) ion channel 3
- naked mole-rat(101722725) acid-sensing (proton-gated) ion channel 3
- domestic cat(101096970) acid-sensing (proton-gated) ion channel 3
- domestic guinea pig(100731464) acid-sensing (proton-gated) ion channel 3
- sheep(101113062) acid-sensing (proton-gated) ion channel 3
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