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SAB4503383

Sigma-Aldrich

Anti-Catalase antibody produced in rabbit

affinity isolated antibody

Synonym(s):

CAT, CATA

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About This Item

MDL number:
MFCD00802760
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 59 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000
immunohistochemistry: 1:50-1:100

NCBI accession no.

P04040

UniProt accession no.

P04040

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CAT(847)

General description

Anti-Catalase Antibody detects endogenous levels of total Catalase protein.
Anti-Catalase Antibody detects endogenous levels of total Catalase protein. Catalase is an important antioxidant enzyme. It is located on human chromosome 11p13. Catalase is a tetrameric heme protein. It is abundantly present in aerobic organisms and most of the mammalian tissues.

Immunogen

The antiserum was produced against synthesized peptide derived from human Catalase.

Immunogen Range: 361-410

Application

Anti-Catalase antibody has been used in immunohistochemical studies, immunoelectron microscopic studies and immunofluorescence studies.

Biochem/physiol Actions

Catalase helps in the clearance of reactive oxygen species. Mutation in catalase (CAT) gene result in the progress of essential hypertension (EH). It helps to convert hydrogen peroxide to water and molecular oxygen.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Influence of A-21T and C-262T genetic polymorphisms at the promoter region of the catalase (CAT) on gene expression.
Khyber S, et al.
Environmental Health and Preventive Medicine, 21(5), 382?386-382?386 (2016)
Free Radicals in Cell Biology
Vidosava B
International Review of Cytology, 237, 57-89 (2004)
Frequent Loss of Heterozygosity on Chromosomes 3p and 17p without VHL or p53 Mutations Suggests Involvement of Unidentified Tumor Suppressor Genes in Follicular Thyroid Carcinoma.
Stefan K G G, et al.
The Journal of Clinical Endocrinology and Metabolism, 82(11), 3684?3691-3684?3691 (1997)
Association of the-844G> A polymorphism in the catalase gene with the increased risk of essential hypertension in smokers.
Bushueva O Y, et al.
Terapevticheski? Arkhiv, 88(9), 50-54 (2016)
The effect of glucagon-like peptide-1 in the management of diabetes mellitus: cellular and molecular mechanisms.
Lotfy M, et al.
Cell and Tissue Research, 358(2), 343-358 (2014)
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