Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

G0902

Sigma-Aldrich

Ginsenoside-Rc from Panax ginseng (Korean ginseng) root

triterpenoid saponin, ≥98% (HPLC)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C53H90O22
CAS Number:
11021-14-0
Molecular Weight:
1079.27
EC Number:
234-253-5
MDL number:
MFCD00133368
UNSPSC Code:
12352201
PubChem Substance ID:
24895029
NACRES:
NA.25

biological source

plant root (Panax ginseng)

Quality Level

200

Assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

storage temp.

2-8°C

SMILES string

C\C(C)=C\CCC(C)(OC1OC(COC2OC(CO)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C

InChI

1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-68-45-41(65)36(60)28(21-56)69-45)24-11-16-52(7)33(24)25(57)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)35(59)27(20-55)71-48)74-46-42(66)38(62)34(58)26(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3

InChI key

JDCPEKQWFDWQLI-UHFFFAOYSA-N

Biochem/physiol Actions

Ginsenoside-Rc exhibits anti-proliferative effects on human breast cancer cell lines and can induce expreβion of the leucine-zipper transcription factor c-fos.
Triterpene saponin found in ginseng.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yang Chu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 919-920, 75-78 (2013-02-16)
Ginsenoside Rc (GRc) is a potential pharmacologically active ingredient isolated from ginseng (Panax ginseng C.A. Meyer, Araliaceae). A simple, rapid and sensitive method for determination of GRc in rat plasma was developed based on liquid chromatography-tandem mass spectrometry (LC-MS/MS). The
Osamu Morinaga et al.
Glycobiology, 15(10), 1061-1066 (2005-06-24)
A method has been devised for the chromatographic resolution of glucosidic compounds, ginseng saponins, on polyethersulphone (PES) membrane. The method results in good resolution and quantitative immunoassay for ginsenoside Rb1 (G-Rb1), G-Rc, and G-Rd in crude extracts of various ginsengs.
Young Joo Lee et al.
Archives of pharmacal research, 26(1), 53-57 (2003-02-06)
We have found that ginsenoside Rc and Re induce c-fos in MCF-7 human breast carcinoma cells at both the mRNA and protein levels. However, neither ginsenoside activated the expression of reporter gene under the control of AP-1/TPA response elements. We
T B Ng et al.
Journal of ethnopharmacology, 16(2-3), 191-199 (1986-06-01)
Ginsenosides Rb2, Rc and Rg1 suppressed corticotropin-induced, dibutyryl cyclic AMP-induced and epinephrine-induced lipolysis with the relative potencies Rb2 greater than Rc greater than Rg1. The inhibition of corticotropin-induced lipolysis by ginsenoside Rg1 could not be overcome by increasing the dose
Y Han et al.
Journal of applied microbiology, 109(3), 792-798 (2010-03-27)
This study examined the transformation pathways of ginsenosides G-Rb(1) , G-Rb(3) , and G-Rc by the fungus Fusarium sacchari. Ginsenosides G-Rb(1) , G-Rb(3) and G-Rc were isolated from leaves of Radix notoginseng, and their structural identification was confirmed using NMR.
View All Related Papers

Chromatograms

application for HPLC

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service