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45607

Supelco

Parathion

PESTANAL®, analytical standard

Synonym(s):

O,O-Diethyl O-(4-nitrophenyl) phosphorothioate, Ethylparathione, Parathion-ethyl

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About This Item

Empirical Formula (Hill Notation):
C10H14NO5PS
CAS Number:
Molecular Weight:
291.26
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CCOP(=S)(OCC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C10H14NO5PS/c1-3-14-17(18,15-4-2)16-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3

InChI key

LCCNCVORNKJIRZ-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 1

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

248.0 °F - closed cup

Flash Point(C)

120 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Inactivation of rat liver cytochrome P-450 by the suicide substrates parathion and chloramphenicol.
J Halpert et al.
Drug metabolism reviews, 12(2), 239-259 (1981-01-01)
Abdul Shafeeuulla Khan et al.
Journal of molecular graphics & modelling, 34, 10-17 (2012-02-07)
The extreme toxicity of organophosphorus nerve agents and pesticides mandates to employ models or simulants in place of the actual compounds in the laboratory. The importance of simulants is known, however, their efficacy for direct comparison with the toxic organophosphorus
Becky J Proskocil et al.
American journal of physiology. Lung cellular and molecular physiology, 304(8), L519-L529 (2013-02-05)
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of functional loss of inhibitory M2 muscarinic receptors
Alejandro A Canales-Aguirre et al.
Nutritional neuroscience, 15(2), 62-69 (2012-02-16)
One of the main concerns regarding organophosphate pesticides (OP) is their possible toxic effects. Doses that do not produce acute toxicity are capable of altering the structure and biochemistry of different tissues and organs by production of reactive oxygen species
Courtney Dunn et al.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19(5), 504-509 (2012-05-19)
Therapies exist for acute organophosphate (OP) exposure but mortality rates remain high (10% to 20%). Currently, treatment focuses on reversing the resultant cholinergic excess effects through the use of atropine. Intralipid fat emulsion (IFE) has been used to treat lipophilic

Protocols

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

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