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850142P

Avanti

16:0-18:1 PI

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium salt), powder

Synonym(s):

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); POPI; PI(16:0/18:1); 110660

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About This Item

Empirical Formula (Hill Notation):
C43H84NO13P
CAS Number:
50730-13-7
Molecular Weight:
854.10
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850142P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850142P-500ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 850142P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP(OC[C@H](OC([C17H33])=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O.[NH4+]

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol (PI) carries myo-inositol in its headgroup. This phospholipid comprises up to 10% of the lipid of eukaryotic cells.

Application

16:0-18:1 PI (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium salt)) has been used as a component in giant unilamellar vesicles (GUVs). It has also been sued as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850142P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850142P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Inositol Phosphate Metabolism
Cellular and Molecular Mechanisms of Inflammation, 153-174 null
Lipid Protein Interactions in Membranes
Yeagle, PL
The Membranes of Cells, 291-334 null
Dorotea Fracchiolla et al.
The Journal of cell biology, 219(7) (2020-05-22)
Autophagy degrades cytoplasmic cargo by its delivery to lysosomes within double membrane autophagosomes. Synthesis of the phosphoinositide PI(3)P by the autophagic class III phosphatidylinositol-3 kinase complex I (PI3KC3-C1) and conjugation of ATG8/LC3 proteins to phagophore membranes by the ATG12-ATG5-ATG16L1 (E3)
Sarah N Sipe et al.
Analytical chemistry, 92(1), 899-907 (2019-11-26)
Development of chemical chaperones to solubilize membrane protein complexes in aqueous solutions has allowed for gas-phase analysis of their native-like assemblies, including rapid evaluation of stability and interacting partners. Characterization of protein primary sequence, however, has thus far been limited.
Na Li et al.
Analytical chemistry, 91(24), 15873-15882 (2019-11-14)
The matrix plays a prominent role in expanding the ability of matrix assisted laser desorption/ionization mass spectrometry (MALDI MS). However, on account of the unclarity of necessary properties of the matrix in MALDI MS, development of a new matrix is
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