700138P

7-dehydrodesmosterol

powder

• Synonym(s): Cholesta-5,7,24-trien-3β-ol
• Empirical Formula (Hill Notation): C₂₇H₄₂O
• CAS Number: 1715-86-2
• Molecular Weight: 382.62
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 1 mg (700138P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 700138P
• shipped in: dry ice
• storage temp.: −70°C
• InChI: 1S/C27H42O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9-10,19,21,23-25,28H,6,8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1
• InChI key: RUSSPKPUXDSHNC-DDPQNLDTSA-N

Description

General description

7-dehydrodesmosterol (7-DHD) is synthesized via the Bloch pathway. 7-DHD serves as a desmosterol synthesis precursor and the enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes this step.

Application

7-dehydrodesmosterol has been used as an internal oxysterol standard in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).

Biochem/physiol Actions

7-dehydrodesmosterol (7-DHD) levels are higher during fetal development and increases with aging. Elevated levels of 7-DHD is associated with Smith-Lemli-Opitz syndrome mouse model. Reduced levels of 7-DHD is observed in shiverer and quaking disorder.

Packaging

5 mL Amber Glass Screw Cap Vial (700138P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids