W253901

γ-Heptalactone

≥98%, FCC, FG

• Synonym(s): (±)-4-Heptanolide, (±)-γ-Propyl-γ-butyrolactone, (±)-Dihydro-5-propyl-2(3H)-furanone
• Empirical Formula (Hill Notation): C₇H₁₂O₂
• CAS Number: 105-21-5
• Molecular Weight: 128.17
• FEMA Number: 2539
• Beilstein: 109569
• EC Number: 203-279-9
• Council of Europe no.: 2253
• MDL number: MFCD00036498
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901126
• Flavis number: 10.020
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Fragrance grade; Halal; Kosher
• Agency: follows IFRA guidelines; meets purity specifications of JECFA
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR 117; FDA 21 CFR 172.515
• Assay: ≥98%
• refractive index: n20/D 1.442 (lit.)
• bp: 61-62 °C/2 mmHg (lit.)
• density: 0.999 g/mL at 25 °C (lit.)
• application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: no known allergens
• Organoleptic: coconut; creamy; sweet
• SMILES string: CCCC1CCC(=O)O1
• InChI: 1S/C7H12O2/c1-2-3-6-4-5-7(8)9-6/h6H,2-5H2,1H3
• InChI key: VLSVVMPLPMNWBH-UHFFFAOYSA-N
• Gene Information: human ... CYP1A2(1544)

Description

General description

γ-Heptalactone is a volatile flavor compound found in mangoes, strawberries, pineapples as well as in some dairy products. It is used as a flavoring agent in the food and cosmetic industry.

Application

• Enzymes with Lactonase Activity against Fungal Quorum Molecules as Effective Antifungals.: This study investigates the potential of lactonase enzymes in combating fungal infections by disrupting fungal communication systems. The findings indicate significant antifungal activity, suggesting applications in developing new antifungal treatments (Efremenko et al., 2024).


• Product study of the reactions of gamma-caprolactone and gamma-heptalactone initiated by OH radicals at 298 K and atmospheric pressure: Formation of acyl peroxynitrates (APN).: This research explores the chemical reactions of gamma-heptalactone with OH radicals, leading to the formation of acyl peroxynitrates, which are significant in atmospheric chemistry and pollution studies (Baptista et al., 2023).


• Effect of gamma-Heptalactone on the Morphology and Production of Monascus Pigments and Monacolin K in Monascus purpureus.: The paper examines how gamma-heptalactone influences the production of bioactive compounds in Monascus purpureus, with implications for food and pharmaceutical industries (Shi et al., 2022).


• RIFM fragrance ingredient safety assessment, gamma-heptalactone, CAS Registry Number 105-21-5.: This safety assessment evaluates gamma-heptalactone as a fragrance ingredient, ensuring its safe use in various consumer products (Api et al., 2019).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315
• Hazard Classifications: Skin Irrit. 2
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves