Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

553751

Sigma-Aldrich

3-Bromo-2-chloropyridine

98%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C5H3BrClN
CAS Number:
52200-48-3
Molecular Weight:
192.44
MDL number:
MFCD00234007
UNSPSC Code:
12352100
PubChem Substance ID:
24879351
NACRES:
NA.22

Assay

98%

form

solid

mp

54-57 °C (lit.)

SMILES string

Clc1ncccc1Br

InChI

1S/C5H3BrClN/c6-4-2-1-3-8-5(4)7/h1-3H

InChI key

HDYNIWBNWMFBDO-UHFFFAOYSA-N

General description

3-Bromo-2-chloropyridine can be synthesized from 3-amino-2-chloropyridine or 2-chloro-3-pyridinamine.

Application

3-Bromo-2-chloropyridine may be used to synthesize:
  • acetylenic dipyridone
  • 3-ethynyl-2-(phenylmethoxy)-pyridine
  • nemertelline
  • ortho-chlorodiheteroarylamine4 or 2-chloro-N-(2,3,7-trimethylbenzo[b]thien-6-yl)pyridin-3-amine

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Use of hydrogen bonds to control molecular aggregation. behavior of dipyridones and pyridone-pyrimidones designed to form cyclic triplexes.
Boucher E, et al.
The Journal of Organic Chemistry, 60(5), 1408-1412 (1995)
Maria-João R P Queiroz et al.
Bioorganic & medicinal chemistry, 14(20), 6827-6831 (2006-07-18)
ortho-Chlorodiarylamines in the 2,3,7-trimethylbenzo[b]thiophene series were prepared in high yields (70-85%) by C-N palladium-catalyzed cross-coupling using P(t-Bu)(3) as ligand and NaOt-Bu as base. A palladium-assisted C-C intramolecular cyclization of the coupling products gave thienocarbazoles and the dechlorinated diarylamines. Studies of
Synthesis of the first thieno-d-carboline: Fluorescence studies in solution and in lipid vesicles.
Queiroz MJRP, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 181(2), 290-296 (2006)
Alexandre Bouillon et al.
The Journal of organic chemistry, 68(26), 10178-10180 (2003-12-20)
Regioselective and univocal Suzuki cross-coupling reactions performed on halopyridinyl boronic acids provide a flexible and versatile route to a multigram scale synthesis of 2,2'-dichloro-3,4'-bipyridine 14, which allows couplings with excess pyridin-3-yl boronic acid to give a new and efficient two-step
Synthesis of novel halopyridinylboronic acids and esters. Part 2: 2, 4, or 5-Halopyridin-3-yl-boronic acids and esters.
Bouillon A, et al.
Tetrahedron, 58(17), 3323-3328 (2002)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service