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278785

Sigma-Aldrich

Triisobutylsilane

99%

Synonym(s):

Tris(2-methylpropyl)silane

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About This Item

Linear Formula:
[(CH3)2CHCH2]3SiH
CAS Number:
6485-81-0
Molecular Weight:
200.44
Beilstein:
1738887
MDL number:
MFCD00010340
UNSPSC Code:
12352103
PubChem Substance ID:
24856831
NACRES:
NA.22

Assay

99%

refractive index

n20/D 1.435 (lit.)

bp

204-206 °C (lit.)

density

0.764 g/mL at 25 °C (lit.)

SMILES string

CC(C)C[SiH](CC(C)C)CC(C)C

InChI

1S/C12H28Si/c1-10(2)7-13(8-11(3)4)9-12(5)6/h10-13H,7-9H2,1-6H3

InChI key

BORQTRQJFUNMBC-UHFFFAOYSA-N

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General description

Triisobutylsilane (TIBS) is a versatile organosilicon compound that finds several applications in organic synthesis. Some of its common applications include desulfurization, deprotection of the N-boc group, and radical reactions.

Application

Triisobutylsilane can be used as a reagent in combination with trifluoroacetic acid (TFA) for the deprotection of the Fmoc functional group.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

228.2 °F - closed cup

Flash Point(C)

109 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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