- Antihypertensive (2-aminoethyl)thiourea derivatives. 2.
Antihypertensive (2-aminoethyl)thiourea derivatives. 2.
Journal of medicinal chemistry (1980-12-01)
J W Tilley, H Ramuz, F Hefti, M Gerold
PMID6779010
RESUMEN
Starting with 2,6-dichlorophenyl isothiocyanate, 1-(2-aminoethyl)-2-cyano-3-(2,6-dichlorophenyl)guanidine (2) was prepared in three steps. In contrast to the corresponding thiourea 1, this compound was essentially inactive as an antihypertensive agent.
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