- Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines.
Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines.
Chemical communications (Cambridge, England) (2010-04-14)
Yong Qian, Gaoyuan Ma, Aifeng Lv, Hai-Liang Zhu, Jing Zhao, Viresh H Rawal
PMID20386849
RESUMEN
Chiral squaramides are highly enantioselective catalysts for Friedel-Crafts reaction of indoles with N-tosyl imines, affording 3-indolyl methanamine products in 85-96% yields and 84-96% ees.
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