Saltar al contenido
Merck

Treatment of acute vivax malaria with tafenoquine.

Transactions of the Royal Society of Tropical Medicine and Hygiene (2004-11-20)
Peter Nasveld, Scott Kitchener
RESUMEN

Tafenoquine is an 8-aminoquiniline related to primaquine with pre-clinical activity against a range of malaria species. We treated two acute cases of vivax malaria with tafenoquine (800 mg over three days) alone, instead of conventional chloroquine (1500 mg over three days) and primaquine (420 mg over 14 days). In addition to the convenience of this regimen, the rapid parasite clearances observed, coupled with a good clinical response and lack of recrudescence or relapse, indicate that further investigation of tafenoquine in the treatment of vivax malaria is warranted.

MATERIALES
Referencia del producto
Marca
Descripción del producto

Sigma-Aldrich
Tafenoquine succinate, ≥95% (HPLC)