- Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride.
Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride.
Chemical communications (Cambridge, England) (2003-03-04)
Hua Fu, Bo Han, Yu-Fen Zhao
PMID12611002
RESUMEN
Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride in pyridine produced adenosine 5'-phosphoramidates in good yields under mild conditions, it is interesting that nucleophilic attack of amino acid methyl esters only occurred on alpha-phosphorus of ADP.