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Merck

Possible pitfalls in the workup of ectopic ACTH secretion illustrated by four rare cases.

BMJ case reports (2019-11-23)
Jorianne Boers, P Christine Oldenburg-Ligtenberg, Aline Me Stades, Mark Jc van Treijen
RESUMEN

In this case report, we highlight four different cases of ectopic adrenocorticotropic hormone (ACTH) secretion with different pitfalls in the diagnostic workup. Ectopic ACTH secretion (EAS) is an uncommon cause of Cushing's syndrome that accompanies a variety of tumours. It is associated with significant morbidity and mortality. This underlines the importance of early and adequate diagnosis. We will review the causes of EAS and their presentation to increase awareness of this rare and progressive disease.

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Sigma-Aldrich
Anti-Corticotropin Releasing Factor antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution