261610

Cyanogen bromide solution

5.0 M in acetonitrile

• Sinónimos: Bromine cyanide, Bromine monocyanide, Bromocyanide, Bromocyanogen, Carbononitridic bromide, Cyanic bromide, Cyanobromide, Cyanogen monobromide
• Fórmula lineal: BrCN
• Número de CAS: 506-68-3
• Peso molecular: 105.92
• Beilstein/REAXYS Number: 1697296
• MDL number: MFCD00011597
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648163
• NACRES: NA.22

Propiedades

• form: liquid
• concentration: 5.0 M in acetonitrile
• solubility: alcohol: freely soluble(lit.); diethyl ether: freely soluble(lit.); water: freely soluble(lit.)
• density: 1.093 g/mL at 25 °C
• functional group: bromo
• storage temp.: 2-8°C
• SMILES string: BrC#N
• InChI: 1S/CBrN/c2-1-3
• InChI key: ATDGTVJJHBUTRL-UHFFFAOYSA-N

Descripción

General description

Cyanogen bromide solution induces template-guided condensation of oligonucleotides only in the presence of N-substituted morpholines. Mechanism of the phosphomonoester group activation by cyanogen bromide in N-substituted morpholine buffers has been investigated.

Application

Cyanogen bromide is a general reagent used to cleave carbon-heteroatom bonds. It is used in the synthesis of organocyanamides from corresponding tertiary amines, which is popularly known as von Braun reaction. CNBr solution is widely used in protein immobilization and cleavage.

Información de seguridad

• pictograms: GHS02,GHS06,GHS05,GHS09
• signalword: Danger
• hcodes: H225,H300 + H310 + H330,H314,H400
• pcodes: P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• supp_hazards: EUH032
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 42.8 °F - closed cup
• flash_point_c: 6 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter