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480959

Sigma-Aldrich

Glycolamide

98%

Synonym(s):

2-Hydroxyacetamide

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About This Item

Linear Formula:
HOCH2CONH2
CAS Number:
Molecular Weight:
75.07
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

mp

118-120 °C (lit.)

SMILES string

NC(=O)CO

InChI

1S/C2H5NO2/c3-2(5)1-4/h4H,1H2,(H2,3,5)

InChI key

TZGPACAKMCUCKX-UHFFFAOYSA-N

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General description

Glycolamide, an isomer of glycine, can be synthesized by the ammonolysis of ethyl glycolate. The conformational analysis of glycolamide has been reported. Its diffusion coefficient in water and partial molal isothermal compressibility has been determined. Its thermodynamic properties have been investigated. Its osmotic and activity coefficients have been obtained.

Application

Glycolamide may be used in the preparation of phosphoglycolamide.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Prasanta K Mohapatra et al.
Inorganic chemistry, 52(5), 2533-2541 (2013-02-12)
Diglycolamide-functionalized calix[4]arenes (C4DGAs) with varying structural modifications were evaluated for actinide complexation from their extraction behavior toward actinide ions such as UO2(2+), Pu(4+), PuO2(2+), and Am(3+) in the room temperature ionic liquid (RTIL) 1-n-octyl-3-methylimidazolium bis(trifluoromethane)sulfonamide (C8mimNTf2). The formation constants were
Jeffrey C Pelletier et al.
Bioorganic & medicinal chemistry, 16(13), 6617-6640 (2008-05-31)
Antagonism of the gonadotropin releasing hormone (GnRH) receptor has shown positive clinical results in numerous reproductive tissue disorders such as endometriosis, prostate cancer and others. Traditional therapy has been limited to peptide agonists and antagonists. Recently, small molecule GnRH antagonists
R Ruhela et al.
Talanta, 85(2), 1217-1220 (2011-07-06)
A precise, sensitive and selective method for the spectrophotometric determination of palladium (II) using N,N,N',N'-tetra(2-ethylhexyl) thiodiglycolamide T(2EH)TDGA as an extractant is described. Palladium (II) forms yellow colored complex with T(2EH)TDGA which exhibits an absorption maximum at ∼ 300 nm. The
New facile synthesis of phosphoglycolohydroxamic acid and other phosphoglycolic acid derivatives.
Weber P, et al.
Tetrahedron Letters, 44(50), 9047-9049 (2003)
Yuji Sasaki et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 21(10), 1171-1175 (2005-11-08)
In order to evaluate the extraction property of new extractants, diglycolamide (DGA) compounds, we investigated the maximum extraction of di-, tri-, and tetravalent metal ions using nitric acid and n-dodecane. The limits of metal concentration (LOC) for Ca(II), Nd(III) and

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