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N5511

Supelco

(−)-Nicotine solution

1.0 mg/mL, analytical standard, for drug analysis

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About This Item

Empirical Formula (Hill Notation):
C10H14N2
CAS Number:
54-11-5
Molecular Weight:
162.23
Beilstein:
5733110
MDL number:
MFCD00006369
UNSPSC Code:
41116107
PubChem Substance ID:
329818656
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

200

concentration

1.0 mg/mL in methanol
1.0 mg/mL

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

SMILES string

CN1CCC[C@H]1c2cccnc2

InChI

1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1

InChI key

SNICXCGAKADSCV-JTQLQIEISA-N

Gene Information

human ... CHRNA3(1136) , CHRNA4(1137) , CHRNB2(1141) , CHRNB4(1143) , CYP2A6(1548) , KCNH1(3756)
mouse ... Chrna7(11441) , Chrnb1(11443)
rat ... Chrna1(79557) , Chrna2(170945) , Chrna4(25590) , Chrna7(25302) , Chrnb2(54239) , Chrnb4(25103)

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Application

(−)-Nicotine solution has been used as a reference standard in the analysis of nicotine in air affected by second hand smoke using ultra performance liquid chromatography (UPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000393724
0000338537
0000338537
0000333984
0000393724

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(−)-Nicotine hemisulfate salt ≥95% (TLC), ~35 % (w/v) in H2O (based on free base)

Sigma-Aldrich

N1019

(−)-Nicotine hemisulfate salt

Assessment of nicotine for second hand smoke exposure in some public places in Romania by UPLC-MS
Bratan A, et al.
Chemistry Central Journal, 8(1), 29-29 (2014)
E-cigarettes, smokers and health policies.
S Nardini et al.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 79(1), 6-7 (2013-06-08)
Jonathan P Winickoff et al.
Pediatrics, 132(1), 109-117 (2013-06-26)
To test whether routine pediatric outpatient practice can be transformed to assist parents in quitting smoking. Cluster RCT of 20 pediatric practices in 16 states that received either CEASE intervention or usual care. The intervention gave practices training and materials
Shunnosuke Handa
Nihon rinsho. Japanese journal of clinical medicine, 71(3), 482-486 (2013-05-02)
For the habitual smokers with nicotine dependence, it is difficult for them to quit smoking. The nicotine replacement therapy (NRT) is a helpful measure for the persons who want to quit smoking. The concept, medication and practice of the NRT
K Vendrell Rankin
Texas dental journal, 130(5), 446-452 (2013-08-08)
Use and awareness of the e-cigarette, also referred to in the literature as an Electronic Nicotine Delivery Device, has dramatically increased since its introduction to the U.S. market in 2007. The regulatory power of the Food and Drug Administration over
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