M18655

4-Methoxyphenol

ReagentPlus^®, 99%

• Synonym(s): p-Methoxyphenol, 4-Hydroxyanisole, 4-MP, HQMME, Hydroquinone monomethyl ether, MEHQ, p-Guaiacol
• Linear Formula: CH₃OC₆H₄OH
• CAS Number: 150-76-5
• Molecular Weight: 124.14
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24896699
• EC Number: 205-769-8
• Beilstein/REAXYS Number: 507924
• MDL number: MFCD00002332
• Assay: 99%

Properties

• vapor density: 4.3 (vs air)
• Quality Segment: 200
• vapor pressure: <0.01 mmHg ( 20 °C)
• product line: ReagentPlus^®
• assay: 99%
• autoignition temp.: 789 °F
• bp: 243 °C (lit.)
• mp: 55-57 °C (lit.)
• SMILES string: COc1ccc(O)cc1
• InChI: 1S/C7H8O2/c1-9-7-4-2-6(8)3-5-7/h2-5,8H,1H3
• InChI key: NWVVVBRKAWDGAB-UHFFFAOYSA-N
• Gene Information: human ... TYR(7299)

Description

Application

4-methoxyphenol may be used in the synthesis of butylated hydroxy anisoles via alkylation with methyl tert-butyl ether over a non-zeolitic solid acidic catalyst. This process is eco-friendly when compared to the Friedel-Crafts alkylation reaction. 4-MP may also react with aqueous nitrous acid to form 2-nitro-4-methoxyphenol and benzoquinone in varying ratios depending on the reaction conditions. 4-MP can be used as a building block in designing β-cyclodextrin 4-methoxyphenol conjugates that can be potential ligands for drug complexation.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317,H319,H412
• pcodes: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves