- Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe.
Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe.
Angewandte Chemie (International ed. in English) (2013-03-21)
Megan K Thorson, Tomas Majtan, Jan P Kraus, Amy M Barrios
PMID23512751
摘要
Buzzing with activity: A hydrogen sulfide selective fluorogenic probe, 7-azido-4-methylcoumarin (AzMC), serves as a highly sensitive assay for cystathionine β-synthase activity, and is suitable for the high-throughput discovery of novel enzyme inhibitors.
材料