重組細胞
expressed in baculovirus infected Sf9 cells
產品線
PRECISIO®
化驗
≥70% (SDS-PAGE)
形狀
buffered aqueous glycerol solution
比活性
11.2-16.8 nmol/min·mg
分子量
~111 kDa (p110α)
~61 kDa (p85γ)
NCBI登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... PIK3CA(5290)
一般說明
PI3K (p110alpha/p55gamma) or Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position which serve as second messengers in growth signaling pathways. PI3K comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in the PI3K has been associated with insulin resistance and plays an important role in glucose homeostasis in vivo. PI3K also plays an essential role in the development and induction of mast cells in normal and pathogenic immune responses.
外觀
Supplied in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, 25% glycerol.
準備報告
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
法律資訊
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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