RAB1378

人CMG-2 ELISA

for serum, plasma and cell culture supernatants

• 分類程式碼代碼: 41116158
• NACRES: NA.32

属性

• 物種活性: human
• 技術: ELISA: suitable
• 輸入: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... ANTXR2(118429)

说明

一般說明

Anthrax toxin receptor (ANTXR2), also known as capillary morphogenesis protein gene-2 (CMG2), is encoded by the gene mapped to human chromosome 24q21. CMG2 is a ubiquitously expressed type I transmembrane protein. It contains von Willebrand A (vWA) domain that is involved in binding lamin and collagen IV.

This ELISA antibody pair detects Human CMG-2. Other species not yet determined.

應用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化／生理作用

Anthrax toxin receptor (ANTXR2)/ capillary morphogenesis protein gene-2 (CMG2) has been implicated in basement-membrane matrix assembly and endothelial cell morphogenesis. CMG2 acts as a chief receptor for anthrax in vivo. It stimulates the anthrax toxin activity by equipping toxin with a high-affinity binding anchor on the cell membrane and a path of entry into the host cell. Mutation in the gene is associated with the development of rare, autosomal recessive disorders called, Juvenile hyaline fibromatosis (JHF) and infantile systemic hyalinosis (ISH).

其他說明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

安全信息

• 象形圖: GHS05
• 訊號詞: Warning
• 危險聲明: H290
• 防範說明: P234 - P390
• 危險分類: Met. Corr. 1
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable