推荐产品
物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8.2 pg/mL
standard curve range: 8.19-2000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... ANGPTL3(27329)
一般說明
Angiopoietin-related protein 3 (ANGPTL3) is a member of the ANGPTL family and is expressed in the liver. The ANGPTL3 gene is mapped on the human chromosome at 1p31.3. Mutations in the ANGPTL3 gene lead to familial combined hypolipidemia, a Mendelian condition that is indicated by lower levels of triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein cholesterol. The ANGPTL3 enzyme-linked immunosorbent assay (ELISA) kit provides for the quantitative measurement of angiopoietin-related protein 3 in cell culture supernatants, plasma, and serum.
應用
请参考Protocol了解详情。
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Fabiana Quagliarini et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(48), 19751-19756 (2012-11-15)
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL
Maria Fernanda Garcés et al.
Scientific reports, 10(1), 21118-21118 (2020-12-05)
This study aimed to determine ANGPTL3 serum levels in healthy young lean and obese non-diabetic men during an oral glucose tolerance test (OGTT) and correlate them with anthropometric, biochemical and hormonal parameters. A case-control study was carried out and 30
Junpeng Ma et al.
Frontiers in oncology, 10, 1382-1382 (2020-09-15)
Meningiomas, as the most common primary tumor of the central nervous system, are known to harbor genomic aberrations that associate with clinical phenotypes. Here we performed genome-wide genotyping for cranial meningiomas in 383 Chinese patients and identified 9,821 copy-number variations
Andrew A Butler et al.
Journal of lipid research, 61(3), 376-386 (2020-01-11)
Angiopoietin-like protein 3 (ANGPTL3) inhibits lipid clearance and is a promising target for managing cardiovascular disease. Here we investigated the effects of a high-sugar (high-fructose) diet on circulating ANGPTL3 concentrations in rhesus macaques. Plasma ANGPTL3 concentrations increased ∼30% to 40%
Nathan O Stitziel et al.
Journal of the American College of Cardiology, 69(16), 2054-2063 (2017-04-08)
Familial combined hypolipidemia, a Mendelian condition characterized by substantial reductions in all 3 major lipid fractions, is caused by mutations that inactivate the gene angiopoietin-like 3 (ANGPTL3). Whether ANGPTL3 deficiency reduces risk of coronary artery disease (CAD) is unknown. The study
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