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物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 2.74-2000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... CCL18(6362)
一般說明
CC chemokine ligand 18 (CCL18) is expressed at high levels in human lung and serum. This CC chemokine can be found in primates only. The CCL18 gene is mapped to the human chromosome 17q11.2.
The Human PARC ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PARC in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Human PARC
應用
请参考Protocol了解详情。
生化／生理作用
C-C motif chemokine ligand 18 (CCL18) has immunological functions and is associated with tumor progression. It is secreted by tumor associated macrophages (TAMs). The protein recruits naive T-cells and dendritic cells, and induces regulatory T-cells. It also acts as a chemokine for helper T lymphocytes and cytotoxic T lymphocytes. CCL18 has been implicated in the pathogenesis of many cancers.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
CCL18 from tumor-cells promotes epithelial ovarian cancer metastasis via mTOR signaling pathway
Qi Wang
Molecular Carcinogenesis (2016)
25th European Photovoltaic Solar Energy Conference and Exhibition / 5th World Conference on Photovoltaic Energy Conversion; 6-10 September 2010; Valencia; Spain; EU PVSEC Proceedings null
Shinichiro Ohshimo et al.
Respiratory medicine, 108(7), 1031-1039 (2014-05-20)
Acute exacerbation (AE) is a major cause of death in idiopathic pulmonary fibrosis (IPF). However, little is known about sensitive biomarkers for predicting AE. The aim of our study was to investigate the significance of KL-6 and CC-Chemokine Ligand 18
Local Concentrations of CC-Chemokine-Ligand 18 Correlate with Tumor Size in Non-small Cell Lung Cancer and Are Elevated in Lymph Node-positive Disease.
Schmid S
Anticancer Research (2016)
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