推荐产品
SMILES 字串
Cl.Cl.OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1
InChI
1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H
InChI 密鑰
MBHNWCYEGXQEIT-UHFFFAOYSA-N
基因資訊
human ... DRD1(1812) , DRD2(1813) , HRH1(3269)
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一般說明
Fluphenazine may be useful for the treatment of schizophrenia.
應用
Fluphenazine dihydrochloride has been used:
- to study its effects as a drug on glioblastoma (GBM) cells
- in fluorescence-activated cell sorting (FACS) analysis, sorting and single-cell stress-survival experiments
- to study its exposure effects on learning and memory in adult rats
生化／生理作用
D1/D2多巴胺受体拮抗剂；吩噻嗪类抗精神病药；H1组胺受体拮抗剂。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Repr. 1A
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Principles of Psychopharmacology for Mental Health Professionals (2006)
Coupling phenotypic persistence to DNA damage increases genetic diversity in severe stress
Yaakov G, et al.
Nature ecology & evolution, 1(1), 0016-0016 (2017)
G Cai et al.
Molecular pharmacology, 56(5), 989-996 (1999-10-26)
The interaction of dopaminergic antagonists with the D(1A) dopamine receptor was assessed in PC2 cells that transiently express this receptor. The maximal binding and dissociation constants for the D(1A) dopamine receptor, using the ligand [(125)I]SCH23982 were 0.38 +/- 0.09 nM
The Effect of Intrauterine Antipsychotic Drug Exposure on Learning and Memory in Adult Rats
Oltulu C and Karadag CH
Klinik Psikofarmakoloji Bulteni-Bulletin of Clinical Psychopharmacology, 26(4), 364-373 (2016)
Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data
Cheng HW, et al.
Cell Death & Disease, 6(5), e1753-e1753 (2015)
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