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Merck
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EMU072781

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Atg12

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

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產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GGCCTCGGAACAGTTGTTTATTTATGTGAATCAGTCCTTTGCCCCTTCCCCAGACCAAGAAGTTGGAACTCTATATGAGTGTTTTGGCAGTGATGGTAAACTGGTCCTGCATTACTGCAAATCCCAGGCATGGGGATGAGCCAGAAATGAACAACTTGATATTTTCACAGAAGAAAAAAAATCAGAGACATTTCGGTGCTGTGGGAAGAGACTTACTATCAAATATTCAGCATGAATCTGTTAGGACCTGTGTTTATGTATAAGAAAACATCATAGAGTATATAGACTAATGAATGAGATTTGTGTCACCATAAAATCATCATGAGAGATTGACGTTAGAGTGTGCCATTACTCCCACACACTCCTGTTCCAGGTCACGTTAGAAAGGAGACTGAAGTTGTATGTGGATTGCAGGTCTCAGGATGACTGAAGGCA

Ensembl | 小鼠類登錄號

ENSMUSG00000032905

NCBI登錄號

NM_026217

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... ATG12(67526) , Atg12(67526)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

12 - Non Combustible Liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Sun-Jung Cho et al.
Autophagy, 11(1), 100-112 (2014-12-09)
Autophagy is one of the main mechanisms in the pathophysiology of neurodegenerative disease. The accumulation of autophagic vacuoles (AVs) in affected neurons is responsible for amyloid-β (Aβ) production. Previously, we reported that SUMO1 (small ubiquitin-like modifier 1) increases Aβ levels.

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