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方案
≥98%
储存温度
2-8°C
SMILES字符串
Br[H].CCSC(N)=N
生化/生理作用
Inhibitor of inducible human, endothelial and neuronal nitric oxide synthetase isozymes.
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
188.6 °F - Solvent
闪点(°C)
87 °C - Solvent
G J Southan et al.
British journal of pharmacology, 114(2), 510-516 (1995-01-01)
1. The induction of a calcium-independent isoform of nitric oxide (NO) synthase (iNOS) and a subsequent enhanced formation of NO has been implicated in the pathophysiology of a variety of diseases including inflammation and circulatory shock. Here we demonstrate that
E P Garvey et al.
The Journal of biological chemistry, 269(43), 26669-26676 (1994-10-28)
S-Ethylisothiourea was a potent competitive inhibitor of human nitric oxide synthase (NOS), with Ki values of 17, 36, and 29 nM for the inducible (i), endothelial (e), and neuronal (n) isozymes, respectively. Unlike some potent inhibitors of NOS, no time
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