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生物源
human plasma
品質等級
形狀
salt-free, lyophilized powder
濃度
≥60% (biuret)
技術
inhibition assay: suitable
儲存溫度
2-8°C
基因資訊
human ... ELA2(1991) , ELANE(1991) , SERPINA1(5265)
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生化／生理作用
丝氨酸蛋白酶抑制剂；抑制胰蛋白酶、胰凝乳蛋白酶和胰腺和粒细胞弹性蛋白酶、以及顶体酶。有效浓度与蛋白酶等摩尔。遗传性 α1-抗胰蛋白酶缺乏的影响和某些自身免疫状态是由体内不受控制的蛋白水解引起的。Direct α1-抗胰蛋白酶替代疗法在1型糖尿病的动物模型中具有应用前景。
≤10 mg可抑制1.0 mg 蛋白活性10,000 BAEE/mg的胰蛋白酶。≤10 mg可抑制约1.0 mg 40-50 BTEE/mg的糜蛋白酶。
注意
含有0.01％NaN3的水溶液可稳定几个月。溶液可在−80 °C下储存，但不应重新冷冻。其在pH 5.5以下不稳定。其可由一些非丝氨酸蛋白酶，以及氧化活性位点的甲硫氨酸残基进行灭活。
準備報告
色谱法制备且部分纯化。
免責聲明
仅供研究使用。本品在法国的科研应用受到监管，包括用于进口和出口活动（法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2）。如《公共卫生法典》所述，购买者（即最终用户）需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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[Figure: see text].
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