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Merck

A5376

Sigma-Aldrich

乙酰水杨酸

≥99.0%

别名:

2-乙酰氧基苯甲酸, O-乙酰水杨酸, ASA, 阿司匹林

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About This Item

线性分子式:
2-(CH3CO2)C6H4CO2H
CAS号:
分子量:
180.16
Beilstein:
779271
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.21

生物源

synthetic

品質等級

化驗

≥99.0%

形狀

powder

顏色

white

pKa (25 °C)

3.5

mp

134-136 °C (lit.)

溶解度

H2O: 10 mg/mL at 37 °C(lit.)
H2O: 3 mg/mL at 25 °C(lit.)
ethanol: 50 mg/mL
aqueous base: decomposes

&epsilon ;(消光係數)

190 at 298 nm in aqueous base at 1 mM
409 at 231 nm in aqueous base at 1 mM
466 at 230 nm in aqueous acid at 1 mM
68 at 278 nm in aqueous acid at 1 mM

SMILES 字串

CC(=O)Oc1ccccc1C(O)=O

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

InChI 密鑰

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

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一般說明

乙酰水杨酸是一种有机化合物,通常被称为阿司匹林。它通过阻止体内引发疼痛、肿胀和发热的化合物的产生来起作用。乙酰水杨酸还在预防动脉中形成血凝块方面发挥重要作用。在研究中,乙酰水杨酸被研究其在氧化应激中的作用,并在癌症研究作为生物标志物。

生化/生理作用

通过抑制环氧化酶(前列腺素H合酶),对COX-1亚型具有更高的选择性,阻止前列腺素的产生。抗血栓作用是由于COX-1在血小板中的抑制作用,阻止血栓形成和血小板聚集。 对结直肠及其他实体肿瘤有化学预防作用。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

482.0 °F

閃點(°C)

250 °C

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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