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Merck

PHR1389

Supelco

异丙安替比林

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

4-Isopropylantipyrine, 1,2-Dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-one, 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, Isopropylphenazone, Propyphenazone

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About This Item

经验公式(希尔记法):
C14H18N2O
CAS号:
分子量:
230.31
Beilstein:
204533
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. P3750000

API 家族

propyphenazone 

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

O=C1C(C(C)C)=C(C)N(C)N1C2=CC=CC=C2

InChI

1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3

InChI 密鑰

PXWLVJLKJGVOKE-UHFFFAOYSA-N

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一般說明

Propyphenazone is a nonsteroidal drug exhibiting anti-inflammatory properties. It is widely used as a mild anesthetic medicine. It belongs to the pyrazolone class of compounds and has been posited to elicit an allergic or pseudo allergic reaction.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Propyphenazone can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA1896 in the slot below. This is an example certificate only and may not be the lot that you receive.

相關產品

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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High-performance Liquid Chromatographic Determination of Paracetamol, Propyphenazone, and Caffeine in Pharmaceutical Formulations
Delvadiya K, et al.
Indian Journal of Pharmaceutical Education and Research, 47(4), 65-72 (2014)
Simultaneous determination of paracetamol, caffeine and propyphenazone in ternary mixtures by micellar electrokinetic capillary chromatography
Emre D and Ozalt?n, Nuran
Journal of Chromatography. B, Biomedical Sciences and Applications, 847(2), 126-132 (2007)
Derivative ratio spectra-zero crossing spectrophotometry and LC method applied to the quantitative determination of paracetamol, propyphenazone and caffeine in ternary mixtures
Dinc E, et al.
Journal of Pharmaceutical and Biomedical Analysis, 26(5-6), 769-778 (2001)
A rapid spectrophotometric method to resolve ternary mixtures of propyphenazone, caffeine, and acetaminophen in tablets
Ozgur MU, et al.
Monatshefte fur Chemie / Chemical Monthly, 133(2), 219-223 (2002)
Sebastian Zühlke et al.
Journal of chromatography. A, 1050(2), 201-209 (2004-10-29)
A new analytical method applying in situ derivatization was developed to enable the extraction of polar drug metabolites from water samples by solid-phase extraction (SPE). An additional derivatization by silylation was used to enhance the sensitivity of analyte detection by

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