生物来源
mouse
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
10AG2, monoclonal
表单
liquid
包含
≤0.1% sodium azide as preservative
种属反应性
human
制造商/商品名称
Calbiochem®
储存条件
do not freeze
同位素/亚型
IgG1
运输
wet ice
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
human ... IKBKB(3551)
一般描述
Immunoaffinity purified mouse monoclonal antibody. Recognizes the ~87 kDa IKKβ protein.
Recognizes the ~87 kDa IKKβ protein in Daudi cells.
This Anti-IKKβ Mouse mAb (10AG2) is validated for use in Immunoblotting for the detection of IKKβ.
免疫原
Human
a recombinant protein consisting of full-length human IKKβ fused to a His•Tag sequence
应用
Immunoblotting (1-4 g/ml, chemiluminescence)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
外形
In PBS, 0.2% gelatin, pH 7.4.
分析说明
Positive Control
Daudi cells
Daudi cells
其他说明
Antibody should be titrated for optimal results in individual systems.
Delhase, M., et al. 1999. Science284, 309.
Li. Q., et al. 1999. Science284, 321.
Didonato, et al. 1997. Nature388, 548.
Lee, F.S., et al. 1997. Cell88, 213.
Malinin, N.L., et al. 1997. Nature385, 540.
Mercurio, F., et al. 1997. Science278, 860.
Regnier, C.H., et al. 1997. Cell90, 373.
Verma, I. And Stevenson, J.K. 1997. Proc. Nat. Acad. Sci. USA94, 11758.
Verma, I.M., et al. 1995. Genes. Dev.9, 2723.
Li. Q., et al. 1999. Science284, 321.
Didonato, et al. 1997. Nature388, 548.
Lee, F.S., et al. 1997. Cell88, 213.
Malinin, N.L., et al. 1997. Nature385, 540.
Mercurio, F., et al. 1997. Science278, 860.
Regnier, C.H., et al. 1997. Cell90, 373.
Verma, I. And Stevenson, J.K. 1997. Proc. Nat. Acad. Sci. USA94, 11758.
Verma, I.M., et al. 1995. Genes. Dev.9, 2723.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Jonathan M Starkey et al.
Diabetes, 55(5), 1252-1259 (2006-04-29)
Evidence of diabetes-induced nuclear factor-kappaB (NF-kappaB) activation has been provided with DNA binding assays or nuclear localization with immunohistochemistry, but few studies have explored mechanisms involved. We examined effects of diabetes on proteins comprising NF-kappaB canonical and noncanonical activation pathways
Tamara P Martin et al.
Cellular signalling, 51, 166-175 (2018-07-31)
Calcium/calmodulin dependent protein kinase IIδ (CaMKIIδ) acts as a molecular switch regulating cardiovascular Ca2+ handling and contractility in health and disease. Activation of CaMKIIδ is also known to regulate cardiovascular inflammation and is reported to be required for pro-inflammatory NF-κB
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