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Merck
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主要文件

MAB8510

Sigma-Aldrich

Anti-Human Metapneumovirus 75.1 Antibody, clone 1B7

clone 1B7, Chemicon®, from mouse

别名:

Metapneumovirus

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified immunoglobulin

克隆

1B7, monoclonal

种属反应性

human

制造商/商品名称

Chemicon®

技术

ELISA: suitable
immunofluorescence: suitable

同位素/亚型

IgG2a

运输

wet ice

特异性

Recognizes Human Metapneumoviruses. Reacts against both A and B antigenic groups and subgroups 1 and 2.

免疫原

Epitope: localized to the M1 protein human metapneumovirus
MPV CAN98-75

应用

Detect Human Metapneumovirus 75.1 using this Anti-Human Metapneumovirus 75.1 Antibody, clone 1B7 validated for use in ELISA & IF.
ELISA
Immunofluorescence:
It is difficult to grow the metapneumovirus in standard cell lines. LLC-MK2 can be used for culture; acetone fixation is recommended. See Ebihara, 2005.

Optimal dilutions must be determined by the end user
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

外形

Protein A purified
Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.

储存及稳定性

Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析说明

Control
Metapneumovirus positive patient sample

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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James B Mahony
Expert review of anti-infective therapy, 8(11), 1273-1292 (2010-11-16)
The appearance of eight new respiratory viruses in the human population in the past 9 years, including two new pandemics (SARS coronavirus in 2003 and swine-origin influenza A/H1N1 in 2009), has tested the ability of virology laboratories to develop diagnostic
Detection of human metapneumovirus in clinical samples by immunofluorescence staining of shell vial centrifugation cultures prepared from three different cell lines.
Landry, ML; Ferguson, D; Cohen, S; Peret, TC; Erdman, DD
Journal of Clinical Microbiology null
Comparison of different cell lines and incubation times in the isolation by the shell vial culture of human metapneumovirus from pediatric respiratory samples.
Jordi Reina,Francesc Ferres,Eva Alcoceba,Aina Mena,Enrique Ruiz de Gopegui,Joan Figuerola
Journal of Clinical Virology null
Tomohiro Ogawa et al.
Frontiers in immunology, 12, 767666-767666 (2021-12-14)
Bronchial epithelial cells are front sentinels eliciting innate and adaptive immunity to respiratory viral pathogens. Recognition of viral double-stranded RNA induces antiviral interferon (IFN) responses in bronchial epithelial cells. Co-inhibitory molecules programmed cell death 1 ligand 1 (PD-L1) and ligand
Akitaka Fujita et al.
Frontiers in immunology, 11, 432-432 (2020-03-29)
Viral infections of the airway can exacerbate respiratory diseases, such as asthma or chronic obstructive pulmonary disease (COPD), and accelerate disease progression. Phosphoinositide 3-kinase (PI3K)δ, a class 1A PI3K, has been studied as a potential target for achieving anti-oncogenic and

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