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Merck
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文件

ABC963

Sigma-Aldrich

Anti-phospho Mitofusin2 Antibody (Ser442)

别名:

Mitofusin-2|Transmembrane GTPase MFN2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

無性繁殖

polyclonal

物種活性

human

技術

inhibition assay: suitable (peptide)
western blot: suitable

一般說明

Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.

免疫原

KLH-conjugated linear peptide corresponding to human phospho Mitofusin2 (Ser442).

應用

Anti-phospho Mitofusin2 Antibody (Ser442) is an antibody against phospho Mitofusin2 (Ser442) for use in Western Blotting, Peptide Inhibition Assay.

品質

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: 1.0 ug/mL of this antibody detected phospho Mitofusin2 (Ser442) in 10 ug of SH-SY5Y cell lysate.

其他說明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1


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