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M-005

Supelco

吗啡标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式（希尔记法）:
C17H19NO3
CAS号:
57-27-2
分子量:
285.34
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

格式

single component solution

儲存溫度

−20°C

SMILES 字串

CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35

InChI

1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1

InChI 密鑰

BQJCRHHNABKAKU-KBQPJGBKSA-N

基因資訊

human ... OPRM1(4988)

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相关类别

一般說明

该认证的分析标准品适用于从疼痛处方监测、临床毒理学研究和尿液药物检测到药物研究和法医分析的各种GC/MS或LC/MS应用。

吗啡是一种天然的酚类生物碱，常被用于止痛和抗炎。吗啡以 MS Contin®、Kadian®、Oramorph® 和 Roxanol 等商品名销售，由于其应用广泛、成瘾性高，也是一种常见的滥用消遣性药物。

應用

该认证标准溶液（CRM）还可作如下用途：
  • 使用电化学测定吗啡的差分脉冲伏安法在极低体积溶液中开发水凝胶修饰碳糊电极（HCPE）
  • 结合磁性分子印迹固相萃取（MMISPE）和高效液相色谱（HPLC）进行尿液中吗啡的定量分析
  • 使用基于 Pt 纳米颗粒修饰碳纳米角（CNHs@PtNP）传感器对人体尿液和血清样品中的吗啡和 3,4-亚甲基二氧甲基苯丙胺（MDMA）进行电化学检测与测量
  • 使用稳定性指示高效液相色谱法结合光电二极管阵列检测器同时测定吗啡和散装纳曲酮及其复合固体剂型
  • 通过红外（IR）光谱和透射电子显微镜（TEM）分析柠檬酸盐覆盖金纳米颗粒（AuNP）聚集的差异，进而对人血清和尿液样本中的吗啡和布洛芬进行比色估计

特點和優勢

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试，以确保准确性和保质期
  • 使用合格的精密天平进行重量准备，以确保最小不确定性
  • 氩气环境下火焰密封，装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式，以提高实验室效率

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Kadian is a registered trademark of Actavis Elizabeth LLC
MS Contin is a registered trademark of Purdue Frederick Company
Oramorph is a registered trademark of AAIPharma, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

分析证书(COA)

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In response.
Alain Gorgeat
Anesthesia and analgesia, 116(6), 1391-1391 (2013-07-12)
Beatrice Setnik et al.
Journal of opioid management, 9(2), 139-150 (2013-05-28)
To evaluate whether intact or crushed doses of an extended-release formulation of morphine sulfate surrounding an inner core of sequestered naltrexone (MSN) induces signs and symptoms of withdrawal in opioid-dependent patients. Randomized, double-blind, two-way crossover study. Single center. Fourteen patients
A Bilir
Clinical and experimental obstetrics & gynecology, 40(1), 118-121 (2013-06-04)
Pain management has a particular importance after Cesarean section. This study was undertaken in order to document the efficacy and side-effects of epidural morphine instead of patient-controlled analgesia technique used for the control of post-cesarean pain during postoperative 24-48 hours.
Thitima Chinachoti et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96(5), 589-594 (2013-06-12)
Presently, in Siriraj Hospital, intrathecal morphine is routinely used in spinal anesthesia for postoperative pain control in more than 600 cases per month with doses lower than 0.3 mg. However, the incidence of side effects is high. This retrospective data
Importance of reducing pain during routine procedures.
Michael C Petty
Journal of the American Veterinary Medical Association, 242(8), 1048-1048 (2013-05-15)
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