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化驗
96% (NT)
形狀
liquid
折射率
n20/D 1.398 (lit.)
bp
93-94 °C/18 mmHg (lit.)
密度
1.101 g/mL at 25 °C (lit.)
運輸包裝
wet ice
儲存溫度
2-8°C
SMILES 字串
CCOC(=O)OC(=O)OCC
InChI
1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3
InChI 密鑰
FFYPMLJYZAEMQB-UHFFFAOYSA-N
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一般說明
焦碳酸二乙酯选择性地与十字形结构的单链环反应。已有研究表明焦碳酸二乙酯可使核糖核酸酶发生不可逆失活。
應用
焦碳酸二乙酯被用作：
- 核酸酶抑制剂，用于从黄化和绿色植物组织中提取未降解的核酸
- 抗微生物添加剂
- 核糖核酸酶抑制剂
- 组氨酸残基修饰剂
- 将亚胺转化为氨基甲酸酯的试剂
蛋白中His及Tyr残基的修饰试剂。用于dsDNA结构破坏的稳健探针，可与完全或部分未堆叠的碱基发生反应。
生化／生理作用
在溶液中浓度约为 0.1% (v/v) 时可使 RNase 失活，从而防止 RNA 被降解。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
156.2 °F - closed cup
閃點（°C）
69 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
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A mechanism of the irreversible inactivation of bovine pancreatic ribonuclease by diethylpyrocarbonate. A general reaction of diethylpyrocarbonate . A general reaction of diethylpyrocarbonate with proteins.
B Wolf et al.
European journal of biochemistry, 13(3), 519-525 (1970-04-01)
Isolation of plant RNA.
R Hodge
Methods in molecular biology (Clifton, N.J.), 28, 37-40 (1994-01-01)
J C Furlong et al.
Nucleic acids research, 14(10), 3995-4007 (1986-05-27)
Diethyl pyrocarbonate reacts with the single-stranded loops of cruciform structures with great selectivity. Adenine bases are carbethoxylated, as a result of which the backbone may be cleaved with piperidine, and the level of chemical modification at each base may be
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Solid-state lithium fast-ion conductors are crucial for safer, high-energy-density all-solid-state batteries, addressing conventional battery limitations.
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