SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
别名:
PAI, PAI-1, PAI1, PLANH1
物种:
Human SERPINE1 (5054), Mouse Serpine1 (18787), Rat Serpine1 (24617), cow SERPINE1 (281375), Zebrafish serpine1 (100136840), domestic guinea pig Serpine1 (100725387), naked mole-rat Serpine1 (101703903), Domestic Rabbit SERPINE1 (100009588), dog SERPINE1 (403476), domestic cat SERPINE1 (100127105)
UniProtKB ID:
基因ID:
- Human(5054) Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(18787) serine (or cysteine) peptidase inhibitor, clade E, member 1
- Rat(24617) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- cow(281375) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Zebrafish(100136840) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- domestic guinea pig(100725387) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- naked mole-rat(101703903) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Domestic Rabbit(100009588) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- dog(403476) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- domestic cat(100127105) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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