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Merck

RBP3

retinol binding protein 3, interstitial

别名:
D10S64, D10S65, D10S66, IRBP, RBPI, RP66
物种:
Human RBP3 (5949), Mouse Rbp3 (19661), Rat Rbp3 (24711), dog RBP3 (489084), cow RBP3 (281443), sheep RBP3 (101115179), domestic cat RBP3 (101091050), domestic guinea pig Rbp3 (100723349), chicken RBP3 (395553)
UniProtKB ID:
P10745, Q5VSR0
基因ID:
  • Human(5949) Summary: Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008]
  • Mouse(19661) retinol binding protein 3, interstitial
  • Rat(24711) retinol binding protein 3, interstitial
  • dog(489084) retinol binding protein 3, interstitial
  • cow(281443) retinol binding protein 3, interstitial
  • sheep(101115179) retinol binding protein 3, interstitial
  • domestic cat(101091050) retinol binding protein 3, interstitial
  • domestic guinea pig(100723349) retinol binding protein 3, interstitial
  • chicken(395553) retinol binding protein 3, interstitial

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Antibodies

货号
说明
物种反应性
应用
HPA041301
Anti-RBP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
WH0005949M1
Monoclonal Anti-RBP3 antibody produced in mouse, clone 4F3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
HPA044239
Anti-RBP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
MABN2592
Anti-RBP3 Antibody, clone mAb5, ,
物种反应性
bovine
应用
electron microscopy
immunoprecipitation (IP)
western blot

esiRNA

货号
说明
物种
EHU020991
MISSION® esiRNA, targeting human RBP3,
物种
human