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Merck

PRPH2

peripherin 2 (retinal degeneration, slow)

别名:
AOFMD, AVMD, CACD2, DS, PRPH, RDS, RP7, TSPAN22, rd2
物种:
UniProtKB ID:
基因ID:
  • Human(5961) Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
  • Mouse(19133) peripherin 2
  • Rat(25534) peripherin 2
  • domestic cat(727697) peripherin 2 (retinal degeneration, slow)
  • sheep(101109569) peripherin 2 (retinal degeneration, slow)
  • cow(280907) peripherin 2 (retinal degeneration, slow)
  • chicken(395899) peripherin 2 (retinal degeneration, slow)
  • naked mole-rat(101702401) peripherin 2 (retinal degeneration, slow)
  • dog(403972) peripherin 2 (retinal degeneration, slow)
  • domestic guinea pig(100713395) peripherin 2 (retinal degeneration, slow)

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Antibodies

货号
说明
物种反应性
应用
抗外周蛋白抗体, serum, Chemicon®,
物种反应性
bovine, human, mouse, pig, rat
应用
immunohistochemistry
western blot
外周蛋白抗体,克隆8G2, culture supernatant, clone 8G2, Chemicon®,
物种反应性
bovine, human, mouse, pig, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-Peripherin-2 Antibody, clone 6B10.1, clone 6B10.1, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
抗-PRPH2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-Peripherin-2 Antibody, clone 5H2, clone 5H2, from mouse,
物种反应性
bovine, mouse
应用
immunofluorescence
radioimmunoassay

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PRPH2,
物种
human