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Merck

MUC1

mucin 1, cell surface associated

别名:
CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
物种:
UniProtKB ID:
基因ID:
  • Human(4582) Summary: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
  • Mouse(17829) mucin 1, transmembrane
  • Rat(24571) mucin 1, cell surface associated
  • dog(448784) mucin 1, cell surface associated
  • naked mole-rat(101702421) mucin 1, cell surface associated
  • domestic cat(101093832) mucin 1, cell surface associated
  • chicken(426412) mucin 1, cell surface associated
  • domestic cat(100294522) mucin 1, cell surface associated
  • cow(281333) mucin 1, cell surface associated
  • domestic guinea pig(100733534) mucin 1, cell surface associated
  • sheep(100294589) mucin 1, cell surface associated
  • sheep(101106133) mucin 1, cell surface associated
  • Domestic Rabbit(100009240) mucin 1, cell surface associated

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ELISA

货号
说明
物种
人碳水化合物抗原15-3/Mucin-1 ELISA试剂盒, for serum, plasma, cell culture supernatant and urine,
物种
human

Antibodies

货号
说明
物种反应性
应用
EMA (E29) Mouse Monoclonal Antibody, ,
物种反应性
human
应用
immunohistochemistry
Anti-MUC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-MUC1 Antibody, clone HMFG2, clone HMFG2, from mouse,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
MUC1 (EP85) Rabbit Monoclonal Primary Antibody, ,
物种反应性
应用
immunohistochemistry
MUC1 (MRQ-17) Mouse Monoclonal Antibody, ,
物种反应性
human
应用
immunohistochemistry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human MUC1,
物种
human