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Merck

KRAS

Kirsten rat sarcoma viral oncogene homolog

别名:
C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
物种:
UniProtKB ID:
基因ID:
  • Human(3845) Summary: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
  • Mouse(16653) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • Rat(24525) Kirsten rat sarcoma viral oncogene
  • Zebrafish(445289) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • sheep(101114005) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • naked mole-rat(101718997) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • chicken(418207) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • dog(403871) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • cow(541140) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • domestic guinea pig(100716262) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

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Antibodies

货号
说明
物种反应性
应用
Anti-Kras Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
western blot
单克隆抗 KRAS 小鼠抗, clone 3B10-2F2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
单克隆抗 KRAS 小鼠抗, clone 4F3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
抗-Pan-Ras (Ab-3) 小鼠mAb (RAS 10), liquid, clone RAS 10, Calbiochem®,
物种反应性
human, mouse, rat
应用
Anti-KRAS antibody, Mouse monoclonal, clone KRAS-A582, purified from hybridoma cell culture,
物种反应性
human
应用
western blot

Proteins

货号
说明
物种
KRAS (Mature Form), Active, PRECISIO® Kinase, recombinant,
物种
human

esiRNA

货号
说明
物种
MISSION® 长非编码 esiRNA, targeting mouse KRAS,
物种
mouse
MISSION® esiRNA, targeting human KRAS,
物种
human