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Merck

HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

别名:
5-HT4, 5-HT4R
物种:
UniProtKB ID:
基因ID:
  • Human(3360) Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
  • Mouse(15562) 5 hydroxytryptamine (serotonin) receptor 4
  • Rat(25324) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • Horse(100034053) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • domestic cat(101088723) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • sheep(101117928) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • cow(317708) 5-hydroxytryptamine (serotonin) receptor 4
  • domestic guinea pig(100135548) 5 hydroxytryptamine (serotonin) receptor 4
  • chicken(416150) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • dog(489198) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • naked mole-rat(101707865) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

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Small Molecule - Agonist

货号
说明
物种
Tegaserod maleate, ≥98% (HPLC),
物种
human
甲氧氯普胺, VETRANAL®, analytical standard,
物种
human
甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard,
物种
human
甲氧氯普胺 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human
甲氧氯普胺 盐酸盐, solid,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
SB-204070 盐酸盐, solid, ≥97% (HPLC),
物种
human
ML 10302, ≥98%, solid,
物种
rat
甲氧氯普胺, VETRANAL®, analytical standard,
物种
human
GR 113808, ≥98% (HPLC), solid,
物种
rat, human
甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-5-HT-4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
Anti-HTR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-HTR4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
dog, human, rabbit
应用
western blot

Small Molecule - Blocker

货号
说明
物种
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human
泽麦定 二盐酸盐, solid,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
氟西汀 盐酸盐, solid,
物种
human
盐酸舍曲林 盐酸盐, ≥98% (HPLC),
物种
human
利血平, ,
物种
human

Small Molecule - Ligand

货号
说明
物种
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Precursor

货号
说明
物种
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human HTR4,
物种
human