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Merck

DHCR24

24-dehydrocholesterol reductase

别名:
DCE, Nbla03646, SELADIN1, seladin-1
物种:
UniProtKB ID:
基因ID:
  • Human(1718) Summary: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • Mouse(74754) 24-dehydrocholesterol reductase
  • Rat(298298) 24-dehydrocholesterol reductase
  • domestic guinea pig(100714000) 24-dehydrocholesterol reductase
  • naked mole-rat(101703975) 24-dehydrocholesterol reductase
  • dog(489573) 24-dehydrocholesterol reductase
  • domestic cat(101098730) 24-dehydrocholesterol reductase
  • Horse(100034055) 24-dehydrocholesterol reductase
  • cow(533726) 24-dehydrocholesterol reductase
  • sheep(101123162) 24-dehydrocholesterol reductase
  • Zebrafish(494102) 24-dehydrocholesterol reductase
  • chicken(424661) 24-dehydrocholesterol reductase

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Antibodies

货号
说明
物种反应性
应用
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-DHCR24 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rat
应用
immunohistochemistry
western blot
Anti-DHCR24 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, human, mouse, rabbit, rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
曲帕拉醇, ≥97% (HPLC), powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Dhcr24,
物种
mouse
MISSION® esiRNA, targeting human DHCR24,
物种
human