CYP11B1
cytochrome P450, family 11, subfamily B, polypeptide 1
别名:
CPN1, CYP11B, FHI, P450C11
物种:
Human CYP11B1 (1584), Mouse Cyp11b1 (110115), Rat Cyp11b1 (500892), sheep CYP11B1 (767576), cow CYP11B1 (282422), domestic guinea pig Cyp11b1 (100135511)
UniProtKB ID:
基因ID:
- Human(1584) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
- Mouse(110115) cytochrome P450, family 11, subfamily b, polypeptide 1
- Rat(500892) cytochrome P450, family 11, subfamily b, polypeptide 1
- sheep(767576) cytochrome P450, family 11, subfamily B, polypeptide 1
- cow(282422) cytochrome P450, subfamily XI B, polypeptide 1
- domestic guinea pig(100135511) cytochrome P450, family 11, subfamily b, polypeptide 1
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Antibodies
货号
说明
物种反应性
应用
Anti-CYP11B1 Antibody, clone 1J14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-CYP11B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Cytochrome P450 11β-Hydroxylase Antibody, clone 11B2-1A4, culture supernatant, clone 11B2-1A4, Chemicon®,
物种反应性
rat
应用
immunohistochemistry
western blot
western blot
ANTI-CYP11B1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
货号
说明
物种
1-(2-氯苯基)-1-(4-氯苯基)-2,2-二氯乙烷, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
物种
human
esiRNA
货号
说明
物种